السلام عليكم ورحمه الله وبركاته
أحب إن ابلغ الجميع باني عضو في National Psoriasis Foundation/USA أو المنظمة العالمية للصدفية واعتقد أن معظم الجميع أعضاء فيها أو يعلمون بها, وحقيقة أنا استفدت منهم الكثير. فهم يرسلون التحذيرات ونشرات التوعية وأخر التطورات . وهنا سوف أحاول إخباركم بأخر المستجدات في هذا المنتدى.
وهذا جدول بآخر تطورات شركات الأدوية وأبحاثها.
Treatments in development for psoriasis and/or psoriatic arthritis
Compiled and updated January 2008
Name
Company
Delivery Mechanism
Mechanism of Action
Phase
Indication
CNTO 1275
Centocor, Inc.
injectable
IL-12/ IL-23 inhibitor
Filed for FDA approval
psoriasis
Etanercept (Enbrel)
Amgen, Inc
injectable
TNF-alpha inhibitor
Filed for FDA approval
pediatric psoriasis
Taclonex gel
Warner Chilcott
topical gel
Vitamin D analog, topical steroid
Filed for FDA approval
psoriasis
ABT874
Abbott Immunology
injectable
IL-12/ IL-23 inhibitor
III
psoriasis
ISA 247
Isotechnika
oral
anti-inflammatory agent
III
psoriasis
Tacrolimus
Astellas
topical
IL-2 and T-lymphocite inhibitor
III
psoriasis
AS210 (Psoraxine )
Astralis, LTD.
injectable
anti-inflammatory agent
II
psoriasis
Becocalcidiol (Asord)
QuatRx Pharmaceuticals Co.
topical
Vitamin D analog
II
psoriasis
Bimosiamose
Revotar BioPharmaceuticals AG
topical
Cell migration inhibitor
II
psoriasis
BMS-582949
Bristol-Myers Squibb
oral
anti-inflammatory agent
II
psoriasis
Calcitriol
Galderma
topical
Active form of Vitamin D
II
psoriasis
CC-10004
Celgene
oral
TNF-alpha inhibitor
II
psoriasis
CEP-701
Cephalon
oral
anti-inflammatory agent
II
psoriasis
Certolizumab (Cimzia)
UCB
injectable
TNF-alpha inhibitor
II
psoriasis
CH-1504
Chelsea Therapeutics International, Ltd.
oral
anti-inflammatory agent
II
psoriasis
CNTO 1275
Centocor, Inc.
injectable
IL-12/ IL-23 inhibitor
II
psoriatic arthritis
CTA018
Cytochroma Inc
topical
Vitamin D analog
II
psoriasis
CTAR398
Cytochroma Inc
topical
Vitamin D analog
II
psoriasis
INCB18424
Incyte Corporation
topical
JAK inhibitor
II
psoriasis
MM-093
Merrimack Pharmaceuticals
oral
anti-inflammatory agent
II
psoriasis
PH-10
Provectus Pharmaceutical
topical
II
psoriasis
Rambazole
Barrier Therapeutics
oral
retinoid
II
psoriasis
RWJ-445380
Alza Corporation
oral
anti-inflammatory agent
II
psoriasis
Recent approvals
CNTO 148 (golimumab)
Centocor, Inc.
injectable
TNF-alpha inhibitor
III
psoriatic arthritis
ملاحضة اول ثلاث ادويه لم توافق عليها هيئه الدواء والغذاء الامريكيه,واخر دواء تمت الموافقه عليه